% Publications of Eric A. Zizzi — https://ericzizzi.com/publications/

@article{ferri-2026-jmolgraphmodel-tas2r,
  author = {Ferri, F. and Cannariato, M. and Pallante, L. and Zizzi, E. A. and Miceli, M. and Deriu, M. A.},
  title = {{Explainable machine learning and deep learning models for predicting TAS2R-bitter molecule interactions}},
  journal = {Journal of Molecular Graphics and Modelling},
  year = {2026},
  volume = {142},
  pages = {109187},
  doi = {10.1016/j.jmgm.2025.109187}
}

@article{cecchi-2026-legalmed-ai,
  author = {Cecchi, R. and Calabrò, F. and Camatti, J. and Santunione, A. L. and Sperti, M. and Zizzi, E. A. and Deriu, M. A.},
  title = {{Artificial intelligence in healthcare: Proposal for a new medico-legal methodology in medical liability}},
  journal = {Legal Medicine},
  year = {2026},
  volume = {80},
  pages = {102764},
  doi = {10.1016/j.legalmed.2025.102764}
}

@inproceedings{pattonieri-2026-era-fracture,
  author = {Pattonieri, E. F. and Gregorini, M. and Tsipourakis, A. and Kassem, K. and Grignano, M. A. and Zizzi, E. A. and Margiotta, E. and Portalupi, V. and Soccio, G. and Stea, E. D. and Deriu, M. A. and Rampino, T.},
  title = {{Explainable Machine Learning for Fracture Risk Assessment in Kidney Transplant Recipients: A Single-Center Experience}},
  booktitle = {63rd ERA Congress, Glasgow},
  year = {2026},
  url = {https://iris.polito.it/handle/11583/3011954}
}

@misc{zizzi-2026-chemrxiv-koff,
  author = {Zizzi, E. A. and Cicero, G. and Gentile, F. and Deriu, M. A.},
  title = {{Kinetics Beyond Pose: A Structure-independent Framework for koff Prediction Across Diverse Protein Families}},
  howpublished = {ChemRxiv},
  year = {2026},
  doi = {10.26434/chemrxiv.15003308/v1},
  note = {Preprint}
}

@inproceedings{zizzi-2026-wcb-protofilaments,
  author = {Zizzi, E. A. and Cannariato, M. and Miceli, M. and Morbiducci, U. and Deriu, M. A.},
  title = {{Structural Determinants of Microtubule Mechanics: A Computational Analysis of Protofilament Architectures}},
  booktitle = {10th World Congress of Biomechanics, Vancouver – Book of Abstracts},
  year = {2026},
  pages = {1070--1072},
  url = {https://iris.polito.it/handle/11583/3015349}
}

@article{zizzi-2025-jrsinterface-microtubules,
  author = {Zizzi, E. A. and Cannariato, M. and Miceli, M. and Morbiducci, U. and Deriu, M. A.},
  title = {{Architecture-encoded mechanics and communication in microtubules: a multiscale computational study}},
  journal = {Journal of the Royal Society Interface},
  year = {2025},
  volume = {22},
  number = {233},
  pages = {20250556},
  doi = {10.1098/rsif.2025.0556}
}

@article{zizzi-2025-nanoscale-rosebengal,
  author = {Zizzi, E. A. and Sztandera, K. and Gorzkiewicz, M. and Buczkowski, A. and Apartsin, E. and Deriu, M. A. and Klajnert-Maculewicz, B.},
  title = {{Molecular interactions driving the complexation of rose bengal by triazine-carbosilane dendrons}},
  journal = {Nanoscale},
  year = {2025},
  volume = {17},
  number = {3},
  pages = {1433--1448},
  doi = {10.1039/d4nr02335h}
}

@inproceedings{santi-2025-endoabstr-testosterone,
  author = {Santi, D. and Spaggiari, G. and Furini, C. and Griseta, V. and Zizzi, E. A. and Granata, A. R. M. and Simoni, M.},
  title = {{Temporal trends in serum testosterone and luteinizing hormone levels indicate an ongoing resetting of hypothalamic-pituitary-gonadal function in healthy men: a systematic review}},
  booktitle = {Endocrine Abstracts},
  year = {2025},
  volume = {110},
  pages = {EP1326},
  doi = {10.1530/endoabs.110.EP1326}
}

@article{santi-2025-jendocrinolinvest-testosterone,
  author = {Santi, D. and Spaggiari, G. and Furini, C. and Griseta, V. and Zizzi, E. A. and Granata, A. R. M. and Simoni, M.},
  title = {{Temporal trends in serum testosterone and luteinizing hormone levels indicate an ongoing resetting of hypothalamic-pituitary-gonadal function in healthy men: a systematic review}},
  journal = {Journal of Endocrinological Investigation},
  year = {2025},
  volume = {48},
  number = {11},
  pages = {2721--2734},
  doi = {10.1007/s40618-025-02671-9}
}

@article{cannariato-2024-acsbiomater-taxol,
  author = {Cannariato, M. and Zizzi, E. A. and Tuszynski, J. A. and Deriu, M. A.},
  title = {{Multiscale Computational Analysis of the Effect of Taxol on Microtubule Mechanics}},
  journal = {ACS Biomaterials Science \& Engineering},
  year = {2024},
  volume = {10},
  number = {9},
  pages = {5666--5674},
  doi = {10.1021/acsbiomaterials.4c00847}
}

@article{truglia-2024-pharmaceuticals-actin,
  author = {Truglia, B. and Carbone, N. and Ghadre, I. and Vallero, S. and Zito, M. and Zizzi, E. A. and Deriu, M. A. and Tuszynski, J. A.},
  title = {{An In Silico Investigation of the Molecular Interactions between Volatile Anesthetics and Actin}},
  journal = {Pharmaceuticals},
  year = {2024},
  volume = {17},
  number = {1},
  pages = {37},
  doi = {10.3390/ph17010037}
}

@article{toro-2024-celldeathdis-coronavirus,
  author = {Toro, A. and Arévalo, A. P. and Pereira-Gómez, M. and Sabater, A. and Zizzi, E. A. and Perbolianachis, P. and Pascual, G. and Lage-Vickers, S. and Pórfido, J. L. and Achinelli, I. and Seniuk, R. and Bizzotto, J. and Sanchis, P. and Olivera, A. and Leyva, A. and Moreno, P. and Costábile, A. and Fajardo, A. and Carrión, F. and Fló, M. and Olivero-Deibe, N. and Rodriguez, F. and Nin, N. and Anselmino, N. and Labanca, E. and Vazquez, E. and Cotignola, J. and Alonso, D. F. and Valacco, M. P. and Marti, M. and Gentile, F. and Cherkasov, A. and Crispo, M. and Moratorio, G. and Gueron, G.},
  title = {{Blood matters: the hematological signatures of Coronavirus infection}},
  journal = {Cell Death \& Disease},
  year = {2024},
  volume = {15},
  number = {11},
  pages = {863},
  doi = {10.1038/s41419-024-07247-8}
}

@article{miceli-2024-proteins-alsin,
  author = {Miceli, M. and Cannariato, M. and Tortarolo, R. and Pallante, L. and Zizzi, E. A. and Deriu, M. A.},
  title = {{Conformational Dynamics and Molecular Characterization of Alsin MORN Monomer and Dimeric Assemblies}},
  journal = {Proteins: Structure, Function, and Bioinformatics},
  year = {2024},
  volume = {92},
  number = {11},
  pages = {1343--1353},
  doi = {10.1002/prot.26728}
}

@article{cannariato-2024-frontmolbiosci-tas2r46,
  author = {Cannariato, M. and Fanunza, R. and Zizzi, E. A. and Miceli, M. and Di Benedetto, G. and Deriu, M. A. and Pallante, L.},
  title = {{Exploring TAS2R46 biomechanics through molecular dynamics and network analysis}},
  journal = {Frontiers in Molecular Biosciences},
  year = {2024},
  volume = {11},
  pages = {1473675},
  doi = {10.3389/fmolb.2024.1473675}
}

@article{cecchi-2024-rimeleg-ai,
  author = {Cecchi, R. and Calabrò, F. and Haja, T. M. and Sperti, M. and Zizzi, E. A. and Deriu, M. A.},
  title = {{Intelligenza Artificiale In Sanità: Proposta Di Una Nuova Metodologia Medico-legale In Materia Di Responsabilità Medica}},
  journal = {Rivista Italiana di Medicina Legale e del Diritto in Campo Sanitario},
  year = {2024},
  number = {3-4},
  pages = {441--462},
  url = {https://iris.polito.it/handle/11583/3001115}
}

@article{cannariato-2024-biomechmodel-network,
  author = {Cannariato, M. and Zizzi, E. A. and Pallante, L. and Miceli, M. and Deriu, M. A.},
  title = {{Mechanical communication within the microtubule through network-based analysis of tubulin dynamics}},
  journal = {Biomechanics and Modeling in Mechanobiology},
  year = {2024},
  volume = {23},
  number = {2},
  pages = {569--579},
  doi = {10.1007/s10237-023-01792-5}
}

@article{pallante-2024-scirep-pocketome,
  author = {Pallante, L. and Cannariato, M. and Androutsos, L. and Zizzi, E. A. and Bompotas, A. and Hada, X. and Grasso, G. and Kalogeras, A. and Mavroudi, S. and Di Benedetto, G. and Theofilatos, K. and Deriu, M. A.},
  title = {{VirtuousPocketome: a computational tool for screening protein–ligand complexes to identify similar binding sites}},
  journal = {Scientific Reports},
  year = {2024},
  volume = {14},
  number = {1},
  pages = {6296},
  doi = {10.1038/s41598-024-56893-7}
}

@article{sztandera-2023-bioelectrochem-oatp,
  author = {Sztandera, K. and Gorzkiewicz, M. and Zizzi, E. A. and Dybczak, N. and Poltorak, L. and Deriu, M. A. and Klajnert-Maculewicz, B.},
  title = {{Cellular uptake of rose bengal is mediated by OATP1B1/1B3 transporters}},
  journal = {Bioelectrochemistry},
  year = {2023},
  volume = {152},
  pages = {108449},
  doi = {10.1016/j.bioelechem.2023.108449}
}

@article{kalra-2023-acscentsci-energy,
  author = {Kalra, A. P. and Benny, A. and Travis, S. M. and Zizzi, E. A. and Morales-Sanchez, A. and Oblinsky, D. G. and Craddock, T. J. A. and Hameroff, S. R. and MacIver, M. B. and Tuszyński, J. A. and Petry, S. and Penrose, R. and Scholes, G. D.},
  title = {{Electronic Energy Migration in Microtubules}},
  journal = {ACS Central Science},
  year = {2023},
  volume = {9},
  number = {3},
  pages = {352--361},
  doi = {10.1021/acscentsci.2c01114}
}

@phdthesis{zizzi-2023-unito-thesis,
  author = {Zizzi, E. A.},
  title = {{Strategies for the molecular-level understanding of small molecule-target interactions and dynamics through tailored computational modelling}},
  school = {Università degli Studi di Torino},
  year = {2023},
  url = {https://hdl.handle.net/2318/2017733}
}

@article{zizzi-2022-iscience-lipid,
  author = {Zizzi, E. A. and Cavaglià, M. and Tuszynski, J. A. and Deriu, M. A.},
  title = {{Alteration of lipid bilayer mechanics by volatile anesthetics: Insights from μs-long molecular dynamics simulations}},
  journal = {iScience},
  year = {2022},
  volume = {25},
  number = {3},
  pages = {103946},
  doi = {10.1016/j.isci.2022.103946}
}

@article{uchida-2022-natcommun-nanocapsules,
  author = {Uchida, N. and Kohata, A. and Okuro, K. and Cardellini, A. and Lionello, C. and Zizzi, E. A. and Deriu, M. A. and Pavan, G. M. and Tomishige, M. and Hikima, T. and Aida, T.},
  title = {{Reconstitution of microtubule into GTP-responsive nanocapsules}},
  journal = {Nature Communications},
  year = {2022},
  volume = {13},
  number = {1},
  pages = {5424},
  doi = {10.1038/s41467-022-33156-5}
}

@article{brigante-2022-eurthyroidj-ml,
  author = {Brigante, G. and Lazzaretti, C. and Paradiso, E. and Nuzzo, F. and Sitti, M. and Tüttelmann, F. and Moretti, G. and Silvestri, R. and Gemignani, F. and Försti, A. and Hemminki, K. and Elisei, R. and Romei, C. and Zizzi, E. A. and Deriu, M. A. and Simoni, M. and Landi, S. and Casarini, L.},
  title = {{Genetic signature of differentiated thyroid carcinoma susceptibility: a machine learning approach}},
  journal = {European Thyroid Journal},
  year = {2022},
  volume = {11},
  number = {5},
  doi = {10.1530/ETJ-22-0058}
}

@article{aminpour-2022-computation-ivermectin,
  author = {Aminpour, M. and Cannariato, M. and Preto, J. and Safaeeardebili, M. E. and Moracchiato, A. and Doria, D. and Donato, F. and Zizzi, E. A. and Deriu, M. A. and Scheim, D. E. and Santin, A. D. and Tuszynski, J. A.},
  title = {{In Silico Analysis of the Multi-Targeted Mode of Action of Ivermectin and Related Compounds}},
  journal = {Computation},
  year = {2022},
  volume = {10},
  number = {4},
  pages = {51},
  doi = {10.3390/computation10040051}
}

@article{zizzi-2022-jbsd-tubulin,
  author = {Zizzi, E. A. and Cavaglià, M. and Tuszynski, J. A. and Deriu, M. A.},
  title = {{Insights into the interaction dynamics between volatile anesthetics and tubulin through computational molecular modelling}},
  journal = {Journal of Biomolecular Structure and Dynamics},
  year = {2022},
  volume = {40},
  number = {16},
  pages = {7324--7338},
  doi = {10.1080/07391102.2021.1897044}
}

@inproceedings{zizzi-2021-bse-anaesthetics,
  author = {Zizzi, E. A. and Cavaglià, M. and Deriu, M. A. and Tuszynski, J. A.},
  title = {{In silico investigation of molecular interactions of Volatile Anesthetics: Effects on phospholipid membranes and subcellular targets}},
  booktitle = {Biomedical Science and Engineering},
  year = {2021},
  volume = {4},
  number = {s1},
  pages = {123--124},
  doi = {10.4081/bse.2021.202}
}

@inproceedings{zizzi-2021-esb-tubulin,
  author = {Zizzi, E. A. and Cavaglià, M. and Deriu, M. A. and Tuszynski, J. A.},
  title = {{Molecular Dynamics And Binding Mechanisms Of Volatile Anesthetics Targeting Human Tubulin}},
  booktitle = {26th Congress of the European Society of Biomechanics (ESB 2021), Milan},
  year = {2021},
  url = {https://iris.polito.it/handle/11583/2940059}
}

@article{sztandera-2021-jmedchem-rosebengal,
  author = {Sztandera, K. and Gorzkiewicz, M. and Dias Martins, A. S. and Pallante, L. and Zizzi, E. A. and Miceli, M. and Bątal, M. and Reis, C. P. and Deriu, M. A. and Klajnert-Maculewicz, B.},
  title = {{Noncovalent Interactions with PAMAM and PPI Dendrimers Promote the Cellular Uptake and Photodynamic Activity of Rose Bengal: The Role of the Dendrimer Structure}},
  journal = {Journal of Medicinal Chemistry},
  year = {2021},
  volume = {64},
  number = {21},
  pages = {15758--15771},
  doi = {10.1021/acs.jmedchem.1c01080}
}

@inproceedings{zizzi-2021-cancerto-dendrimers,
  author = {Zizzi, E. A. and Pallante, L. and Miceli, M. and Sztandera, K. and Bątal, M. and Tuszynski, J. A. and Deriu, M. A.},
  title = {{PAMAM and PPI dendrimers as potential anti-cancer drug carriers: a computational investigation}},
  booktitle = {CancerTO - Nanoscience in Cancer Immunotherapy},
  year = {2021},
  url = {https://iris.polito.it/handle/11583/2940092}
}

@inproceedings{pallante-2021-cancerto-colchicine,
  author = {Pallante, L. and Zizzi, E. A. and Miceli, M. and Grasso, G. and Huczynski, A. and Tuszynski, J. A. and Deriu, M. A.},
  title = {{Understanding the molecular binding mechanism of colchicine derivatives targeting βIII human tubulin isotype}},
  booktitle = {CancerTO - Nanoscience in Cancer Immunotherapy},
  year = {2021},
  url = {https://iris.polito.it/handle/11583/2973878}
}

@article{gaetani-2020-frontcelldevbiol-mechanosensing,
  author = {Gaetani, R. and Zizzi, E. A. and Deriu, M. A. and Morbiducci, U. and Pesce, M. and Messina, E.},
  title = {{When Stiffness Matters: Mechanosensing in Heart Development and Disease}},
  journal = {Frontiers in Cell and Developmental Biology},
  year = {2020},
  volume = {8},
  pages = {334},
  doi = {10.3389/fcell.2020.00334}
}